Regional Centres of Expertise (RCEs) were developed as sites for participatory learning and action within the United Nations Decade of Education for Sustainable Development (DESD), opening up more collaborative and inclusive learning spaces towards more just and sustainable ways of life now and in the future. Some of the contours of these emergent education processes of collaborative learning-to-change as they relate to African heritage knowledge in the context of social innovation are developing in many RCE contexts today. The Education for Sustainable Development Programme at UNU-IAS has worked with RCEs across the African continent and in particular southern Africa to create a new publication showcasing a series of case studies in this regard.